广西海洋药物重点实验室

联系方式

E-mail: XXBai2014@163.com

 研究方向

 海洋红树来源微生物资源的挖掘、活性代谢产物的发现和药物先导化合物筛选

 教育背景与工作经历

 2024.12-至今     广西中医药大学       副研究员

2020.07-2024.11              广西中医药大学       助理研究员       

2017.09-2020.06              海南师范大学        天然产物化学    博士       

 2014.09-2017.06             海南师范大学        天然产物化学    硕士

 主持项目

 1、 2024年第一批广西科技人才专项“八桂之光”访学研修项目，2025.04-2026.04，在研，主持；

 2、 广西自然科学基金面上项目，2023GXNSFAA026313，2023.06-2026.05，在研，主持；

 3、 2024年广西中医药大学杰出青年基金项目，2024JQ001，2024.11-2027.10，在研，主持；

 4、 广西青年自然科学基金项目，2021GXNSFBA220072，2021.12-2024.11，结题，主持；

5、 广西高校中青年教师科研基础能力提升项目，2021KY0318，2021.01-2022.12，结题，主持；

近五年代表性论文 (#共同第一作者，*通讯作者)

 1.Yu-Wang, Guang-Ping Cao, Xin-Jian Qu, Yong-Hong Liu, Xiang-Xi Yi, Cheng-Hai Gao*, Meng Bai*. Bioactive Cyclodepsipeptides from Cocultured Mangrove-Derived Aspergillus sp. and Penicillium sp. Journal of Natural Products, 2025, 88, 9, 2239-2246. doi.org/10.1021/acs.jnatprod.5c00752. (SCI 二区)

2.Jia-Lang Xia, Jian-Yun Liu, Kai Liu, Yue-Yao Li, Meng Bai*, Cheng-Hai Gao*, Xiang-Xi Yi*. Journal of Natural Products, 2025, 88, 8, 1980-1987. doi.org/10.1021/acs.jnatprod.5c00673. (SCI 二区)

3.Jia-Li He, Yu Wang, Xiang-Xi Yi, Yu-Man Gan, Yong-Hong Liu, Cheng-Hai Gao*, Kai Liu*, Meng Bai*. Bioactive Sesterterpenoids from the Mangrove-derived Aspergillus sp. GXIMD 03023. Journal of Natural Products, 2025, 88: 1201-1207. doi.org/10.1021/acs.jnatprod.5c00182. (SCI二区) 

4.姜悦，王宇，易湘茜，高程海，刘永宏， 曹沛，白猛*. 近40年真菌代谢产物中环状四肽、五肽和六肽研究进展. 中国抗生素，2025，50: 363-382.

5.Yue Jiang, Fan An, Yu-Man Gan, Kai Liu, Yong-Hong Liu, Cheng-Hai Gao, Pei Cao, Xiang-Xi Yi*, Meng Bai*. Asperhydrindane A, a new hydrindane derivate isolated from a mangrove-derived fungi Aspergillus terreus GXIMD 03158. Natural Product Research, 2025, doi: 10.1080/14786419.2025.2456670. (SCI三区)

6.Jia-Li He#, Xiao-Dong Jiang#, Yu-Man Gan, Xin-Jian Qu, Xiang-Xi Yi, Yong-Hong Liu, Cheng-Hai Gao*, Meng Bai*. Cadophorin C, a new cyclic heptapeptide isolated from a mangrove-derived fungus Penicillium sp. GXIMD 03101. Natural Product Research, 2024, doi: 10.1080/14786419.2024.2425796. (SCI三区)

7.Guang-Ping Cao#, Guo-Qiang Huang#, Guang-Ying Chen, Xiang-Xi Yi, Xue-Sheng Wang, Feng-Jiao Wei, Cai-Qiong Zhu, Cheng-Hai Gao, Yong-Hong Liu*, Meng Bai*, Millmerranones G, a meroterpene isolated from a mangrove-derived fungus Aspergillus sp. GXIMD 03004, Natural Product Research, 2024, doi: 10.1080/14786419.2024.2402460. (SCI三区)

8.Jia-Li He, Chang-Jing Chen, Yong-Hong Liu, Cheng-Hai Gao, Rui-Ping Wang, Wen-Fei Zhang*, Meng Bai*. Austins-type meroterpenoids from the fungi reported in the last five decades: a review. [J]. Journal of Fungi, 2024, 10: 162. (SCI二区)

9.Yu Wang, Guang-ping Cao, Yu-man Gan, Xiao Lin, Xiang-xi Yi, Long-yan Zhao, Yong-hong Liu, Cheng-hai Gao*, Meng Bai*. New cyclic pentapeptides from the mangrove-derived Aspergillus fumigatus GXIMD 03099. Marine Drugs, 2024, 22: 282. (SCI二区)

10.Chang Xu, Guang-ping Cao, Hong Zhang, Meng Bai*, Xiang-Xi Yi*, Xin-jian Qu*. Avellanin A has an antiproliferative effect on TP-induced RWPE-1 cells via the PI3K-Akt signalling pathway. Marine Drugs, 2024, 22: 275. (SCI二区)

11.Guang-ping Cao, Jia-lang Xia, Long-Yan Zhao, Zhen-zhou Tang, Xiao Lin, Yong-hong Liu, Cheng-hai Gao, Kai Liu*, Meng Bai*. Penicixanthene E, a new xanthene isolated from a mangrove-derived fungus Penicillium sp. [J]. The Journal of Antibiotics, 2022, 75: 526-529. (SCI四区)

12.Meng Bai*, Cheng-Hai Gao, Kai Liu, Long-Yan Zhao, Zhen-Zhou Tang, Yong-Hong Liu*. Two new benzophenones isolated from a mangrove-derived fungus Penicillium sp. [J]. The Journal of Antibiotics, 2021, 74(11): 821-824. (SCI四区)

13.Yu-man Gan#, Jia-lang Xia#, Long-yan Zhao, Kai Liu, Zhen-zhou Tang, Bing-yao Huang, Yong-hong Liu, Cheng-hai Gao*, Meng Bai*. Two new isocoumarins isolated from a mangrove-derived Penicillium sp. [J]. Phytochemistry Letters, 2022, 50: 21-24. (SCI四区)

14.Meng Bai, Jia-Li He, Cheng-hai Gao, Fei-Xiang Xiong, Ya Yang, Wei-Chan Yang, Yong-hong Liu*, Wen-Fei Zhang*. SECONDARY METABOLITES FROM Bacillus thuringiensis HS66 [J], Chemistry of Natural Compounds, 2022, 58(2): 381-383. (SCI四区)

15.Meng Bai, Cai-Juan Zheng*, Guang-Ying Chen*. Austins-Type Meroterpenoids from a Mangrove-Derived Penicillium sp. [J]. Journal of Natural Products, 2021, 84(8): 2104-2110. (SCI二区)

16.Yu-man Gan#, Meng Bai#, Xiao Lin, Kai Liu, Bing-yao Huang, Xiao-dong Jiang, Yong-hong Liu*, Cheng-hai Gao*. Improvement of macrolactins production by the genetic adaptation of Bacillus siamensis A72 to saline stress via adaptive laboratory evolution[J]. Microbial cell factories, 2022, 21(1): 147. (SCI二区）

17.Shou-Yuan Wu, Zi-Ming Chen, Qi Zhou*, Guo-Ling Huang, Zhong-Liu Zhou, Meng Bai*. Structurally diverse sulphur-containing amides from Glycosmis craibii with their potential antiproliferative activities, Fitoterapia, 2022, 165: 105418. (SCI三区)

18.安凡, 姜悦, 王宇, 曹广萍, 高程海, 刘永宏, 易湘茜*, 白猛*. 红树老鼠簕内生真菌Aspergillus terreus GXIMD 03158次级代谢产物研究[J]. 热带海洋学报, 2024, 43(5): 41-48.

19.谭玉莹，曹广萍，黄炯丽，李秋庭，唐振洲，刘永宏，高程海*，白猛*。红树老鼠簕来源内生青霉Penicillium sp. GXIMD 03101的次级代谢产物研究[J], 广西科学, 2022, 29(05): 839-845.

20.Shou-Yuan Wu#, Meng-Bai#, Qi-Zhou, Xu-Hua Nong, Guang-Ying Chen, Si-Yu Zhao, Chang-Ri Han*, Xiao-Ping Song*. Phenolic glycosides from the stems of Homalium stenophyllum, Chinese Journal of Natural Medicines, 2021, 19(3): 225-230. (SCI二区)

申请或授权国家发明专利

1.白猛, 刘永宏, 高程海, 刘锴, 黄炳耀, 唐振洲, 林霄. 一种红树内生真菌中二苯甲酮类化合物及其制备方法与应用。授权号：ZL 2021 1 0232241.9，授权公告：CN113072442B，授权公告日：2023年03月21日。 

2.白猛, 高程海, 刘永宏, 唐振洲, 赵龙岩. 一种红树内生真菌中萜类化合物及其制备方法与应用。授权号：ZL 2023 1 0394600.X，授权公告：CN116444536B，授权公告日：2024年06月28日。

3.白猛, 曲鑫建, 蒋晓东, 甘雨满, 易湘茜, 高程海. 环七肽类化合物在制备治疗前列腺增生药物中的应用。申请号：CN202411024651.4，申请时间：2024年07月29日。

4.白猛，王宇，曲鑫建，甘雨满，易湘茜，高程海。一类红树内生真菌来源的环肽类化合物及其制备方法与应用。申请号：202510614182.X，申请时间：2025年05月13日。