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师资队伍

张振伟

张振伟，男，博士，副教授，硕士研究生导师，2017年7月起在广西中医药大学药学院药物化学教研室从事本科生及硕士研究生的《药物化学》、《药学专业英语》和《药物化学专论》等课程的教学工作。入选“广西高等学校千名中青年骨干教师培育计划”，香港中文大学化学系访问学者，中国科学院广州生物医药与健康研究院博士后，中国民族医药学会健康产业分会常务理事，中国化学会会员。主持广西自然科学基金3项、广西中医药大学校级课题多项；参与国家自然科学基金2项、广西科技重大专项1项、广西自然科学基金3项。在J. Am. Chem. Soc.等学术期刊上发表论文20余篇。　 　

研究方向：药物分子的设计合成与活性评价研究；新型有机小分子催化剂的设计合成与应用研究；中药化学成分及其结构修饰、活性评价研究。

联系方式：charliezh@163.com

欢迎各位同学报考我校中药化学和药物化学专业研究生！

教研室人员信息表

已发表的研究论文： 　 　  

(1) Kin Boon Gan, Rong-Lin Zhong*, Zhen-Wei Zhang*, and Fuk Yee Kwong*. Atropisomeric phosphine ligands bearing C−N axial chirality: Applications in enantioselective Suzuki−Miyaura cross-coupling towards the assembly of tetra-ortho-substituted biaryls. J. Am. Chem. Soc.2022, 144, 14864-14873. (被列为JACS同期亮点文章)

(2) Ning Lin*, Qiu-Xiang Wei, Li-Hua Jiang, Yan-Qiu Deng, Zhen-Wei Zhang*, Qing Chen. Asymmetric Michael addition of malononitrile with chalcones via rosin-derived bifunctional squaramide. Catalysts, 2020, 10, 14; doi:10.3390/catal10010014.　

(3) Wen-Run Zhu (#), Zhen-Wei Zhang (#), Wei-Hua Huang, Ning Lin*, Qing Chen*, Kai-Bin Chen, Bi-Chuan Wang, Jiang Weng, Gui Lu*. Asymmetric synthesis of vicinally bis(trifluoromethyl)-substituted 3,3’-pyrrolidinyl spirooxindoles via organocatalytic 1,3-dipolar cycloaddition reactions. Synthesis, 2019, 51, 1969-1979.　

(4) Wang Xia, Zhen-Wei Zhang, Yongsu Li, Xiaoding Jiang, Hao Liang, Yaqi Zhang, Rihui Cao, Liqin Qiu*. Enantioselective synthesis of chiral heterocyclic biaryls via asymmetric Suzuki-Miyaura cross-coupling of 3-bromopyridine derivatives. Org. Biomol. Chem., 2019, 9, 2351-2355.　　

(5) Wen-Run Zhu, Qing Chen, Ning Lin*, Kai-Bin Chen, Zhen-Wei Zhang, Gang Fang, Jiang Weng, Gui Lu*. Organocatalytic Michael/cyclization cascade reactions of 3-isothiocyanato oxindoles with 3-trifluoroethylidene oxindoles: approach for the synthesis of 3′-trifluoromethyl substituted 3,2′-pyrrolidinyl-bispirooxindoles. Org. Chem. Front., 2018, 5, 1375-1380. 　　

(6) Hui-Xuan Chen, Yaqi Zhang, Yuyang Zhang, Xuefeng He, Zhen-Wei Zhang, Hao Liang, Wenhuan He, Xiaoding Jiang, Xiangmeng Chen, Liqin Qiu*. Synthesis of six-membered spirooxindoles via a chiral Brønsted acid-catalyzed asymmetric intramolecular Friedel–Crafts reaction. RSC Adv., 2018, 8, 37035-37039.　

(7) Lichun Zhao, Xue Wang, Junxiu Li, Xiaoming Tan, Lanlan Fan, Zhenwei Zhang, Jing Leng*. Effect of cyclocarya paliurus on hypoglycemic effect in Type 2 diabetic mice. Med. Sci. Monit., 2019, 25, 2976-2983.　

(8) Xin Zhao (#*), Zhen-Wei Zhang (#), Wei Cui, Shengwei Chen, Yang Zhou, Jianghong Dong, Yanling Jie, Junting Wan, Yong Xu*, Wenhui Hu*. Identification of camphor derivatives as novel M2 ion channel inhibitors of influenza A virus. Med. Chem. Comm., 2015, 6, 727-731. (现已更名为：RSC Medicinal Chemistry)　

(9) Ning Lin, Yan-Qiu Deng, Zhen-Wei Zhang, Qian Wang, Gui Lu*. Asymmetric synthesis of chiral β-hydroxy-α-amino acid derivatives by organocatalytic Aldol reaction of isocyanoesters with β,γ-unsaturated α-ketoesters. Tetrahedron: Asymmetry, 2014, 25, 650-657.　　

(10) Yan-Qiu Deng, Zhen-Wei Zhang, Ya-Hui Feng, Albert S. C. Chan, Gui Lu*. Enantioselective Michael reaction of nitroalkanes onto nitroalkenes catalyzed by cinchona alkaloid derivatives. Tetrahedron: Asymmetry, 2012, 23, 1647-1652.　

(11) Zhen-Wei Zhang, Gui Lu*, Miao-Miao Chen, Ning Lin, Yong-Bo Li, Tamio Hayashi, Albert S. C. Chan*. Organocatalytic asymmetric mannich-type reaction of N-Sulfonylimines with isocyanoesters leading to optically active 2-imidazolines. Tetrahedron: Asymmetry, 2010, 21, 1715-1721.