陈豪
陈豪，男，广西中医药大学讲师。2015年7月毕业于北京中医药大学制药工程专业并获学士学位，2018年7月毕业于广西中医药大学中药学专业并获硕士学位，2022年7月毕业于成都中医药大学中药药理学专业并获博士学位。目前从事中药剂型及其评价相关领域研究与开发，现主要承担中药学专业《中药药剂学》相关课程教学。
发表论文：
1. Chen H, Tang X, Li J, et al. IL-17 crosses the blood-brain barrier to trigger neuroinflammation: a novel mechanism in nitroglycerin-induced chronic migraine. J Headache Pain. 2022;23(1):1.
2. Chen H, Yuan J, Hao J, et al. α-Humulene inhibits hepatocellular carcinoma cell proliferation and induces apoptosis through the inhibition of Akt signaling. Food Chem Toxicol. 2019;134:110830.
3. Chen H, Hao J, Wen Y, et al. Data of cytotoxicity, p53 and Akt downstream proteins and physiological indexes in hepatocellular carcinoma cells or HepG2-bearing nude mouse model administered by α-Humulene. Data Brief. 2020;29:105325.
4. Chen H, Yang J, Hao J, et al. A Novel Flavonoid Kushenol Z from Sophora flavescens MediatesmTOR Pathway by Inhibiting Phosphodiesterase and Akt Activity to Induce Apoptosis in Non-Small-Cell Lung Cancer Cells. Molecules. 2019;24(24):4425.
5. Chen H, Zhou B, Yang J, et al. Essential Oil Derived From Eupatorium adenophorum Spreng. Mediates Anticancer Effect by Inhibiting STAT3 and AKT Activation to Induce Apoptosis in Hepatocellular Carcinoma. Front Pharmacol. 2018;9:483.
6. Li X, Wen W, Li P, Chen H, et al. Mitochondrial Protection and Against Glutamate Neurotoxicity via Shh/Ptch1 Signaling Pathway to Ameliorate Cognitive Dysfunction by Kaixin San in Multi-Infarct Dementia Rats. Oxid Med Cell Longev. 2021;2021:5590745.
7. Yang Jequ, Chen Hequ, Wang Q, et al. Inhibitory Effect of Kurarinone on Growth of Human Non-small Cell Lung Cancer: An Experimental Study Both in Vitro and in Vivo Studies. Front Pharmacol. 2018;9:252. (IF 5.810)
8. Song P, Chen H, Ma X, et al. Cytotoxic compounds from the seeds of Sophora alopecuroides L. Natural Product Communications, 2018, 13(8), 997-1000.
9. Hu Y, Ke L, Chen H, et al. Natural material-decorated mesoporous silica nanoparticle container for multifunctional membrane-controlled targeted drug delivery. Int J Nanomedicine. 2017;12:8411-8426. Published 2017 Nov 22.
10. Wen Y, Lv Y, Hao J, Chen H, et al. Two new compounds of Penicillium polonicum, an endophytic fungus from Camptotheca acuminata Decne. Nat Prod Res. 2020;34(13):1879-1883.
11. Huang Y, Hao J, Tian D, Chen H, et al. Antidiabetic Activity of a Flavonoid-Rich Extract From Sophora davidii (Franch.) Skeels in KK-Ay Mice via Activation of AMP-Activated Protein Kinase. Front Pharmacol. 2018;9:760.
12. Yang J, Xu C, Chen H, et al. In vitro and in vivo antitumor effects of the diterpene-enriched extract from Taxodium ascendens through the mitochondrial-dependent apoptosis pathway. Biomed Pharmacother. 2017;96:1199-1208.
13. Wang Q, Pan L, Chen H, Mi Huang, Kaiwen Guo, Xinzhou Yang. Essential oil from Carpesium abrotanoides L. induces apoptosis via activating mitochondrial pathway in hepatocellular carcinoma cells. Current Medical Science, 2018, 38(6): 1045-1053
14. 陈豪, 杨洁, 杨新洲,李余钊,周蓓,袁经权.紫茎泽兰抗肝癌活性研究[J].中药材, 2018, 05: 1211-1214.
15. 文琰章，吕静南，陈豪，郝吉，麻新华，黄密，杨洁，杨新洲, 林亲雄.
矮坨坨共生菌Fusarium oxysporum活性代谢产物研究[J]. 华中师范大学学报（自然科学版）, 2018, 7: 25-27.
16. 周蓓，陈豪，吴丽丽，吴燕春. 蛤蚧对S180 荷瘤小鼠Th1/Th2免疫细胞平衡的影响[J]. 亚太传统医药, 2016, 12(09): 11-13.
参与项目基金：
“宣阳解郁，通络止痛 ”法防治偏头痛的循证评价及机制研究，国家重点研发计划“中医药现代化研究 ”重点专项，2019YFC1709704
基于链接“糖代谢-小胶质细胞极化”关键信号琥珀酸/SUCNR1途径的加味芎归汤“益智”机制研究，面上项目，82074150
民族药石上柏作用于喉癌COX-2和EGFR 多靶标的活性成分及作用机制研究, 面上项目，81774000
基于STAT-3靶点的泽兰属两种外来入侵植物抗肝癌药效物质基础及作用机理研究, 地区科学基金项目, 81660656
基于GLUT4和SGLT2双靶点的槐属药用植物抗糖尿药效物质基础及作用机制研究，面上项目，81573561
其他获奖：
第二届中国“互联网+”大学生创新创业大赛广西选拔赛中荣获银奖。
第二届中国“互联网+”大学生创新创业大赛校内选拔赛中荣获一等奖。
2016年广西大学化学化工学院第十届学术论坛“校外分论坛”中荣获优秀奖
